
A New Class of Lipids for Advanced Therapeutics
NovoArc has developed a proprietary technology platform for producing highly pure, semi‑synthetic tetraether lipids inspired by nature’s most robust biological membranes. These lipids exhibit unique structural properties that improve bioavailability, enhance formulation stability, and address key limitations of conventional lipid delivery systems. Our technology spans the complete value chain, from lipid biosynthesis and extraction to purification, targeted functionalization, and formulation into advanced lipid nanoparticles (LNPs) and liposomal systems.

Why NovoArc Lipids?
Better Delivery. Improved Stability. Greater Design Freedom.
• Enhanced bioavailability and formulation performance
• Exceptional membrane stability based on tetraether lipid architecture
• Customizable lipid structures tailored to specific therapeutic needs
• Compatible with diverse therapeutic modalities, including nucleic acids, proteins, peptides, and small molecules
• Potential to enable oral delivery of therapeutics traditionally limited to injection
• Scalable and reproducible manufacturing following Quality-by-Design principles
• Enhanced bioavailability and formulation performance
• Exceptional membrane stability based on tetraether lipid architecture
• Customizable lipid structures tailored to specific therapeutic needs
• Compatible with diverse therapeutic modalities, including nucleic acids, proteins, peptides, and small molecules
• Potential to enable oral delivery of therapeutics traditionally limited to injection
• Scalable and reproducible manufacturing following Quality-by-Design principles

How our Platform Works
From Lipid Design to Drug Delivery
1. Lipid Production
Proprietary, scalable production of tetraether lipids through controlled bioprocesses.
2. Lipid Purification & Engineering
Extraction, purification, and proprietary chemical modification to generate highly defined lipid building blocks.
3. Formulation Development
Integration into liposomes and lipid nanoparticles optimized for specific therapeutic cargos.
4. Therapeutic Delivery
Stable and effective delivery of nucleic acids, proteins, peptides, and small molecules across multiple administration routes.
1. Lipid Production
Proprietary, scalable production of tetraether lipids through controlled bioprocesses.
2. Lipid Purification & Engineering
Extraction, purification, and proprietary chemical modification to generate highly defined lipid building blocks.
3. Formulation Development
Integration into liposomes and lipid nanoparticles optimized for specific therapeutic cargos.
4. Therapeutic Delivery
Stable and effective delivery of nucleic acids, proteins, peptides, and small molecules across multiple administration routes.
Fields of application
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